agomelatine (Standpharm)

Agomelatine is an atypical antidepressant medication primarily indicated for the treatment of major depressive disorder (MDD). Developed by Servier and marketed as a generic by Standpharm under the name Agorid, it possesses a unique pharmacological profile as a potent agonist at melatonin MT1 and MT2 receptors and a selective antagonist at serotonin 5-HT2C receptors. By targeting these receptors, agomelatine helps to resynchronize disrupted circadian rhythms, which are a hallmark of clinical depression. It is noted for its lack of significant effect on serotonin levels, which contributes to a lower incidence of common antidepressant side effects such as sexual dysfunction and weight gain.

Brand names

AGORID-StandpharmAgoridValdoxanThymanax

Other names

agomelatine