Drug intelligence / Profile preview

Agrippal S1

Development stage
Phase 3
Lead developer
Novartis
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular, Subcutaneous
01

Overview

Agrippal S1 is a trivalent inactivated influenza vaccine designed for the prophylaxis of influenza, especially in individuals at increased risk of influenza-associated complications. It contains purified surface antigens (haemagglutinin and neuraminidase) from three influenza virus strains propagated in fertilized hen’s eggs and inactivated with formaldehyde. The vaccine complies with WHO recommendations for seasonal influenza vaccination. It is administered as a 0.5 ml suspension via intramuscular or deep subcutaneous injection, typically provided in pre-filled syringes. The vaccine may contain trace residues of egg proteins, kanamycin sulfate, neomycin sulfate, formaldehyde, cetyltrimethylammonium bromide (CTAB), polysorbate 80, and other excipients used during manufacturing.

Brand names
Agrippal S1
Other names
Influenza-virus-vaccine-Begrivac-CSLBegrivac vaccine suspension for injection 0.5ml pre-filled syringes
02

Targets

BCR (Immunoglobulin G B Cell Receptor)Influenza virus haemagglutinin and neuraminidaseγδ TCR (T-cell receptor)HA (Hemagglutinin)Neuraminidase

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