Drug intelligence / Profile preview

AgX100

Development stage
Unknown
Lead developer
Theragenics
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Implantation
01

Overview

AgX100 is an iodine-125 (I-125) radioactive brachytherapy seed used for the treatment of localized prostate cancer. Manufactured by Theragenics Corporation and distributed by Accelyon (now BXTA), the device consists of tiny titanium capsules containing the radioisotope iodine-125, which are permanently implanted into the prostate gland. It delivers low-dose rate (LDR) brachytherapy, providing localized radiation that targets tumor tissue while minimizing damage to surrounding healthy organs. The iodine-125 isotope has a half-life of approximately 60 days, after which the radioactivity reduces significantly and the seeds remain inert in the body. The device is characterized according to AAPM Task Group 43 protocols for precise dosimetric delivery.

Brand names
AgX100AgX-100AgX 100
Other names
iodine-125 radioactive seediodine125 radioactive seediodine 125 radioactive seedI-125 seedI125 seedI 125 seedradioactive seed implant
02

Targets

DNA

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