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AH2-15c
- Development stage
- Unknown
- Lead developer
- Sichuan University
01
Overview
AH2-15c: sourced facts only. name: "We herein disclose a new potent and selective ALKBH2 inhibitor (AH2-15c), which showed an IC50 value of 0.031 ± 0.001 μM in a fluorescence polarization (FP) assay and exhibited more than 200-fold selectivity towards ALKBH2 versus other AlkB subfamily members." [PMID:39571461]; target: "We herein disclose a new potent and selective ALKBH2 inhibitor (AH2-15c), which showed an IC50 value of 0.031 ± 0.001 μM in a fluorescence polarization (FP) assay and exhibited more than 200-fold selectivity towards ALKBH2 versus other AlkB subfamily members." [PMID:39571461]; developer: "Key Laboratory of Drug Targeting and Drug Delivery System of Ministry of Education, West China School of Pharmacy, Sichuan University, Chengdu, Sichuan, 610041, China." [PMID:39571461]
02
Targets
ALKBH2 (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2)
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