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AHB-201

Development stage: Preclinical
Lead developer: AusperBio
Modality: Split/Subunit Vaccines → Inactivated Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics, Peptide-based Cancer Vaccines → Cancer Vaccines → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Single-strand DNA → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Modified DNA Oligonucleotides → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics
Administration: Parenteral

Overview

AHB-201 is an antisense oligonucleotide (ASO) therapeutic vaccine being developed by AusperBio for the treatment of chronic hepatitis B. It is designed to target all hepatitis B virus (HBV) RNA, aiming to stimulate the immune system and potentially achieve a functional cure for chronic HBV infection. The drug acts as an immunostimulant and represents a synthetic vaccine approach within the broader class of antisense oligonucleotides. As of late 2024 and early 2025, it remains in preclinical or early research stages with no orphan drug designation[1][2][9].

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