aidi + fluorouracil + leucovorin calcium + oxaliplatin

This is a combination therapy consisting of Aidi injection, fluorouracil, leucovorin calcium (also known as folinic acid), and oxaliplatin. The regimen is primarily used in the treatment of advanced colorectal cancer. Fluorouracil is an antimetabolite that inhibits DNA synthesis; leucovorin calcium enhances the binding of fluorouracil to its target enzyme, increasing its efficacy; oxaliplatin is a platinum-based chemotherapeutic agent that forms DNA crosslinks and inhibits replication and transcription. Aidi injection is a traditional Chinese medicine formulation containing extracts from cantharidin, astragalus, ginseng, and acanthopanax senticosus; it has been studied for its potential to reduce chemotherapy toxicity and improve quality of life when combined with standard regimens like FOLFOX (fluorouracil/leucovorin/oxaliplatin)[3]. Clinical studies suggest that adding Aidi injection to FOLFOX may reduce gastrointestinal side effects and leukopenia while enhancing clinical benefit response[3].