Drug intelligence / Profile preview

aidi injection

Development stage
Phase 4
Lead developer
Guizhou Yibai Pharmaceutical
Administration
Intravenous, Intraperitoneal
01

Overview

Aidi injection is a modernized Chinese herbal injection developed by Guizhou Yibai Pharmaceutical. It is a complex formulation containing extracts from four traditional Chinese medicines: *Panax ginseng* (Ginseng Radix et Rhizoma), *Astragalus mongholicus* (Astragali Radix), *Eleutherococcus senticosus* (Acanthopanacis Senticosi Radix Et Rhizoma Seu Caulis), and *Mylabris phalerata* (Cantharis). The preparation is primarily used in China as an adjuvant therapy for various malignancies, including hepatocellular carcinoma, non-small cell lung cancer, and colorectal cancer. Its mechanism of action involves inhibiting tumor cell proliferation, inducing apoptosis, and modulating the immune system. Key active components identified include cantharidin, ginsenosides (Rb1, Rg1), and astragalosides (IV). It is often used in combination with chemotherapy (e.g., doxorubicin, paclitaxel) to enhance clinical efficacy and reduce treatment-related toxicities such as leukopenia and gastrointestinal reactions.

Brand names
Aidi Injection艾迪注射液
Other names
ADI
02

Targets

CASP3 (Caspase-3)HSP90AA1 (Heat shock protein HSP90-alpha)JUN (Transcription factor Jun)MAPK14 (p38 mitogen-activated protein kinase alpha)TP53 (Cellular Tumor Antigen p53 R175H)VEGFA (Vascular endothelial growth factor A)FOS (Activator Protein 1)TNFA (Tumor necrosis factor alpha (soluble))

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