Drug intelligence / Profile preview

Aikeqing

Development stage
Preclinical
Lead developer
China Academy of Chinese Medical Sciences
Administration
Oral
01

Overview

**Aikeqing** is an orally administered multi-herb traditional Chinese medicine preparation formulated as a capsule and investigated as an adjunct to highly active antiretroviral therapy for HIV infection and acquired immune deficiency syndrome. Its composition includes botanical constituents standardized analytically using icariin, polydatin, glycyrrhizic acid, and baicalin as marker compounds. No single direct molecular target or validated target-level mechanism has been established. In clinical studies it was evaluated for reducing HAART-associated toxicity and resistance-related concerns, while a SHIV89.6-infected Chinese rhesus macaque study reported reduced plasma viral load with early high-dose treatment. ([chictr.org.cn](https://www.chictr.org.cn/showproj.html?proj=5855))

Other names
ACAikeqing CapsuleAKQ艾可清艾可清胶囊
02

Targets

Receptor activator of nuclear factor kappa-B–TNF receptor-associated factor 6 protein–protein interaction interface

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