Drug intelligence / Profile preview

AJ-4

Development stage
Preclinical
Lead developer
Guizhou Medical University
01

Overview

AJ-4: sourced facts only. name: "After in vitro evaluations, the compound AJ-4 was screened as the most remarkable compound with potent inhibitory activities against GSK-3β (IC50: 4.7 nM) and AChE (IC50: 2.97 μM)." [PMID:42320199]; target: "After in vitro evaluations, the compound AJ-4 was screened as the most remarkable compound with potent inhibitory activities against GSK-3β (IC50: 4.7 nM) and AChE (IC50: 2.97 μM)." [PMID:42320199]; developer: "State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine & School of Pharmaceutical Sciences, Guizhou Medical University, Guian New District, 561113, China." [PMID:42320199]; stage: "With favorable pharmacokinetic characteristics and tissue distribution, AJ-4 obviously ameliorated scopolamine-induced learning and memory impairments and alleviated hippocampal neuronal injury in AD mice." [PMID:42320199]

02

Targets

GSK3 (Glycogen synthase kinase 3 beta)

Beyond the preview

Go deeper on AJ-4.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on AJ-4.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call