Drug intelligence / Profile preview

ajwain seed extract

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

Ajwain seed extract is a botanical preparation derived from the seeds of *Trachyspermum ammi* (also known as carom or bishop's weed), a plant in the Apiaceae family. The extract is rich in phenolic compounds, most notably thymol, which is responsible for much of its biological activity. In the context of oncology research, ajwain seed extract has demonstrated potent antiproliferative effects against various breast cancer cell lines, including T-47D, MDA-MB-231, and BT-474. Recent studies have explored enhancing its efficacy through acid hydrolysis (to convert glycosides into more active aglycones) and utilizing exosomal delivery platforms, such as bovine milk or colostrum exosomes, to overcome challenges related to poor oral bioavailability and uptake.

Other names
Trachyspermum ammi extractcarom seed extractbishop's weed extract

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