Drug intelligence / Profile preview

AK-068

Development stage
Unknown
Lead developer
University of Michigan
01

Overview

AK-068: sourced facts only. name: "Starting from a STAT6 ligand with Ki = 3.5 μM binding affinity, we obtained AK-068 with Ki = 6 nM to STAT6 and at least >85-fold binding selectivity over STAT5." [PMID:39311434]; target: "Starting from a STAT6 ligand with Ki = 3.5 μM binding affinity, we obtained AK-068 with Ki = 6 nM to STAT6 and at least >85-fold binding selectivity over STAT5." [PMID:39311434]; developer: "Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States." [PMID:39311434]

02

Targets

STAT6 (Signal Transducer and Activator of Transcription 6)

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