Drug intelligence / Profile preview

AK-1286

Development stage
Phase 1
Lead developer
Yingli Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

AK-1286 is an investigational small molecule drug that acts as a PARP inhibitor. It is being developed for the treatment of advanced solid tumors. The drug is currently in Phase 1 clinical trials, where its safety, tolerability, pharmacokinetics, and preliminary efficacy are being evaluated in patients with advanced solid tumors. The primary objective of these studies is to determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D) following single and multiple oral administrations[2][3]. AK-1286 was initially developed by Shanghai Yingli Pharmaceutical.

02

Targets

PARP (PARP family)

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