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Akeli
- Development stage
- Phase 2
- Lead developer
- Ankang Zhengda Pharmaceutical
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Akeli (阿克力) is a traditional Chinese medicine (TCM) capsule developed by Shaanxi Ankang Jiren Pharmaceutical for the treatment of type 2 diabetes mellitus. It is specifically indicated for patients presenting with Qi-Yin deficiency syndrome, a common pattern in TCM diagnosis for diabetes characterized by symptoms such as thirst, fatigue, and night sweats. The drug has undergone Phase 2 clinical testing in China (CTR20132962) to evaluate its safety and efficacy in lowering blood glucose levels, both as a standalone treatment and in comparison or combination with the sulfonylurea glipizide. Like many TCM formulations, Akeli likely functions through a multi-target mechanism involving various botanical compounds that improve insulin sensitivity and metabolic balance, although its specific molecular targets are not typically defined in standard Western pharmacological terms.
- Brand names
- Akeli
- Other names
- Akeli capsule阿克力胶囊
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