Drug intelligence / Profile preview

Akeli

Development stage
Unknown
Lead developer
Ankang Zhengda Pharmaceutical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Akeli (阿克力) is a traditional Chinese medicine (TCM) capsule developed by Shaanxi Ankang Jiren Pharmaceutical for the treatment of type 2 diabetes mellitus. It is specifically indicated for patients presenting with Qi-Yin deficiency syndrome, a common pattern in TCM diagnosis for diabetes characterized by symptoms such as thirst, fatigue, and night sweats. The drug has undergone Phase 2 clinical testing in China (CTR20132962) to evaluate its safety and efficacy in lowering blood glucose levels, both as a standalone treatment and in comparison or combination with the sulfonylurea glipizide. Like many TCM formulations, Akeli likely functions through a multi-target mechanism involving various botanical compounds that improve insulin sensitivity and metabolic balance, although its specific molecular targets are not typically defined in standard Western pharmacological terms.

Brand names
Akeli
Other names
Akeli capsule阿克力胶囊

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