Drug intelligence / Profile preview

AKL-T01 + stimulant medication

Development stage
Unknown
Lead developer
Akili Interactive
Modality
Small Molecules
Administration
Oral
01

Overview

AKL-T01 + stimulant medication refers to the combined use of the EndeavorRx digital therapeutic with standard-of-care pharmacological stimulants (such as methylphenidate or amphetamine derivatives) for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD). AKL-T01 is an FDA-authorized medical device software that employs the Selective Stimulus Management Engine (SSME) to deliver specific sensory stimuli and simultaneous motor challenges designed to target and improve neural networks involved in attentional control. Stimulant medications function primarily by increasing synaptic concentrations of dopamine and norepinephrine through reuptake inhibition or promoted release. Clinical data, including the STARS-Adjunct study, indicate that the addition of AKL-T01 to stable stimulant regimens provides incremental improvements in ADHD-related impairment and attention without increasing the side effect profile of the medication.

Other names
AKL-T01 plus stimulantsAKL-T-01 plus stimulantsAKL-T 01 plus stimulantsEndeavorRx + stimulant medication
02

Targets

NET (Norepinephrine Transporter)DAT (Dopamine plasma membrane transport protein)

Beyond the preview

Go deeper on AKL-T01 + stimulant medication.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on AKL-T01 + stimulant medication.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call