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AKM Lab-01

Development stage
Phase 1
Lead developer
AKM Labs
Modality
Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

**AKM Lab-01** is a novel strain of the probiotic bacterium *Akkermansia muciniphila* developed for oral administration as an enteric-coated formulation (34B TFU/day). It is being investigated in a randomized, double-blind, placebo-controlled trial involving 60 participants with hypercholesterolemia to assess its safety and efficacy in reducing cholesterol levels through modulation of the gut microbiome. *A. muciniphila* is recognized for its role in regulating metabolic functions, improving gut barrier integrity, and combating obesity and metabolic disorders by degrading mucin and producing short-chain fatty acids that influence host metabolism and immune responses. The strain demonstrates promising probiotic attributes, including safety for human use, and targets conditions like hypercholesterolemia, obesity, and related metabolic diseases.[1][11][13][17]

Brand names
Akkermansia muciniphila AKM Lab-01
Other names
Akkermansia muciniphila AKM Lab-01
02

Targets

MUC2 (Mucin-2)

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