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AKVANO vehicle formulation 1 is a water-free, sprayable vehicle control developed by Lipidor AB, utilizing their proprietary AKVANO technology. This lipid-based delivery system is designed for topical application, where selected lipids are dissolved in a volatile solvent that evaporates rapidly upon contact with the skin, leaving a thin, non-greasy lipid film. As a vehicle formulation, it contains the components of the AKVANO platform but lacks an active pharmaceutical ingredient (API). It was specifically utilized as a placebo comparator in Phase I clinical trials to evaluate the antipsoriatic efficacy and safety of calcipotriol-loaded AKVANO formulations in patients with psoriasis vulgaris.
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