Drug intelligence / Profile preview

AL014

Development stage
Discontinued
Lead developer
Alector
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

**AL014** is an investigational **monoclonal antibody** developed by **Alector** for **Alzheimer's disease**. Public company materials describe it as targeting **MS4A4A**, a microglia-associated transmembrane protein in the MS4A locus linked to Alzheimer's disease genetic risk, with the intended goal of modulating microglial biology in a therapeutically beneficial direction. Available pipeline and drug-database sources indicate the program was in preclinical development and is now **discontinued**, with no evidence of marketing approval or an established commercial product identity.

02

Targets

MS4A4A (Membrane-spanning 4-domains subfamily A member 4A)

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