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AL1
- Development stage
- Preclinical
- Lead developer
- Nexbiome Therapeutics
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
01
Overview
AL1 is a preclinical therapeutic candidate being developed by Nexbiome Therapeutics for the treatment of conditions related to innate immunity. Developed using Nexbiome's proprietary engineered microbiome platform, AL1 is designed to leverage live biotherapeutic products (LBPs) to modulate the host's innate immune system. The program aims to address therapeutic needs in the innate immunity space, although specific indications and molecular targets remain proprietary. The development is currently in the preclinical stage, utilizing the company's platform for engineering commensal microbes to produce or induce specific therapeutic responses within the host environment.
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