Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
AL2846 + FOLFIRI
- Development stage
- Unknown
- Lead developer
- Chia Tai-Tianqing Pharmaceutical Group
- Modality
- Small Molecules
- Administration
- Oral, Intravenous
01
Overview
AL2846 + FOLFIRI is an investigational **combination therapy** for advanced or metastatic colorectal cancer, studied in clinical trials. It consists of **AL2846**, administered orally as a capsule, and the standard FOLFIRI chemotherapy regimen. FOLFIRI contains folinic acid (leucovorin), fluorouracil (5-FU), and irinotecan, and is given intravenously. AL2846's mechanism of action is not disclosed in the current trial registry, but FOLFIRI works by disrupting DNA synthesis and inhibiting topoisomerase I, leading to cancer cell death. The regimen aims to improve disease control rates and progression-free survival for metastatic colorectal cancer patients[3][1].
- Other names
- AL2846 + FOLFIRI
02
Targets
MET (Mesenchymal-epithelial transition factor receptor)TOP1 (DNA Topoisomerase I)TS (Thymidylate synthase)
Beyond the preview
Go deeper on AL2846 + FOLFIRI.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on AL2846 + FOLFIRI.