AL5424

AL5424 is a synthetic small molecule compound belonging to the class of organic compounds known as sulfanilides. It has been studied in the context of drug discovery and development and is structurally characterized as (4R)-4-hydroxy-2-(4-methoxyphenyl)-1,1-dioxo-3H,4H-1λ6,7,2-thieno[3,2-e][1λ6,2]thiazine-6-sulfonamide. The mechanism of action for AL5424 involves inhibition of carbonic anhydrase II (CA-II), an enzyme that catalyzes the reversible hydration of carbon dioxide and plays a role in fluid secretion regulation in tissues such as the eye. Inhibition of CA-II is relevant for conditions like glaucoma and other diseases where modulation of fluid balance or acid-base homeostasis is therapeutic[1][3][5].

Other names

(4R)-4-hydroxy-2-(4-methoxyphenyl)-1,1-dioxo-3H,4H-1λ6,7,2-thieno[3,2-e][1λ6,2]thiazine-6-sulfonamide