Drug intelligence / Profile preview

AL8326

Development stage
Phase 3
Lead developer
Advenchen Laboratories
Modality
Small Molecules
Administration
Oral
01

Overview

AL8326 is an orally administered, small molecule, multi-targeted tyrosine kinase inhibitor under development for the treatment of various cancers. It inhibits Aurora kinase B, fibroblast growth factor receptors (FGFRs), and vascular endothelial growth factor receptors (VEGFRs), leading to antimitotic, antiangiogenic, and antineoplastic effects. The drug is being investigated primarily for small cell lung cancer (SCLC) in late-stage clinical trials and has also been studied in advanced solid tumors and non-small cell lung cancer. Developed by Advenchen Laboratories, AL8326 aims to block key signaling pathways involved in tumor growth and angiogenesis[1][2][3][5][7].

02

Targets

VEGFR (VEGFR family)FGFR (FGFR family)AURKB (Aurora kinase B)

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