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Alanyl glutamine is a dipeptide composed of the amino acids alanine and glutamine. It is used primarily as a nutritional supplement, especially in clinical settings for patients with nutritional deficiencies, short-term fluid replacement after trauma, critical illness, surgery, and inflammatory bowel disease. Alanyl glutamine provides a stable form of glutamine that supports protein synthesis, preserves muscle mass by inhibiting muscle breakdown and increasing muscle protein synthesis, improves electrolyte and water absorption in the intestines, enhances gut barrier function, and supports immune function. Its mechanism involves serving as a source of both alanine and glutamine to support metabolic needs during stress or illness[1][4][5][6][8].
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