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albendazole + vitamin c
- Development stage
- Unknown
- Lead developer
- GSK
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
- Administration
- Oral, Intravenous
01
Overview
Albendazole + vitamin C is a non-standardized combination of two agents: albendazole, a broad-spectrum benzimidazole anthelmintic used to treat various helminth infections, and vitamin C (ascorbic acid), an essential nutrient with antioxidant properties. Albendazole acts by binding to the colchicine-sensitive site of tubulin in parasites, inhibiting microtubule polymerization and glucose uptake, leading to energy depletion and parasite death[2][6]. Vitamin C functions as an antioxidant and is involved in numerous physiological processes including immune function. There are no known clinically significant interactions between these two agents[1]. This combination does not represent a recognized pharmaceutical product or fixed-dose formulation but may be co-administered for specific clinical or research purposes.
- Other names
- albendazole and vitamin calbendazole plus vitamin c
02
Targets
TUBB (Tubulin (alpha and beta subunits))
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