Drug intelligence / Profile preview

albiglutide + alpha-glucosidase inhibitor

Development stage
Unknown
Lead developer
GSK
Modality
Small Molecules, Recombinant Proteins and Enzymes
Administration
Subcutaneous, Oral
01

Overview

**Albiglutide + alpha-glucosidase inhibitor** is a combination therapy for type 2 diabetes mellitus in which **albiglutide**, a glucagon-like peptide 1 receptor agonist (GLP-1 RA), is administered alongside an **alpha-glucosidase inhibitor** (AGI) such as acarbose, miglitol, or voglibose. Albiglutide acts by mimicking the incretin hormone GLP-1, thereby enhancing glucose-dependent insulin secretion and suppressing glucagon secretion. Alpha-glucosidase inhibitors function by inhibiting enzymes (alpha-glucosidases) in the small intestine, thus slowing carbohydrate digestion and attenuating postprandial glucose spikes. The combined use targets multiple glycemic control mechanisms: fasting and especially postprandial hyperglycemia. This combination has been studied in patients inadequately controlled on oral antidiabetic monotherapy, where it has been shown to improve HbA1c and fasting plasma glucose with a favorable safety profile and minimal hypoglycemia risk[1][5][3].

Other names
albiglutide plus alpha-glucosidase inhibitor
02

Targets

GLP1R (GLP-1R)Sucrase-Isomaltase

Beyond the preview

Go deeper on albiglutide + alpha-glucosidase inhibitor.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on albiglutide + alpha-glucosidase inhibitor.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call