Drug intelligence / Profile preview

albiglutide + digoxin

Development stage
Unknown
Lead developer
GSK
Modality
Small Molecules, Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
Administration
Subcutaneous, Oral
01

Overview

This is a combination of **albiglutide**, a recombinant protein-based glucagon-like peptide-1 receptor (GLP-1R) agonist, and **digoxin**, a cardiac glycoside used in heart failure and atrial fibrillation. Albiglutide is designed for type 2 diabetes mellitus to improve glycemic control through glucose-dependent insulin secretion and slowed gastric emptying. Digoxin increases cardiac contractility and controls heart rate via inhibition of Na⁺/K⁺-ATPase, enhancing vagal tone to the heart. There is no established combination product or unique clinical indication for co-formulated albiglutide and digoxin; both are co-administered when clinically appropriate in patients needing both diabetes and cardiac therapy.

Brand names
LanoxinTanzeum
02

Targets

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