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Albumin platelet-rich fibrin
- Development stage
- Phase 3
- Lead developer
- Mansoura University
- Modality
- Bone Marrow MSCs → Mesenchymal Stem Cells → Adult Stem Cells → Stem Cell Therapies → Cell Therapies, Bone Marrow HSCs → Hematopoietic Stem Cells → Adult Stem Cells → Stem Cell Therapies → Cell Therapies
- Administration
- Topical
01
Overview
Albumin platelet-rich fibrin (Alb-PRF) is an autologous biologic material developed for regenerative medicine, specifically evaluated by Mansoura University for enhancing healing after mandibular third molar extractions. It is produced by mixing the patient's own liquid platelet-rich fibrin (PRF) with heated, denatured albumin derived from platelet-poor plasma (PPP). This process creates a stable, long-lasting fibrin-albumin scaffold that persists for 4-6 months, significantly longer than traditional PRF. The matrix serves as a reservoir for the sustained release of growth factors, platelets, and leukocytes, which work together to promote tissue regeneration, reduce postoperative pain and swelling, and accelerate wound healing at the extraction site.
- Brand names
- Bio-PRF
- Other names
- Alb-PRF matrixAlbumin-enriched platelet-rich fibrinAlbumin-PRF
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