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albuterol + ipratropium bromide + methylprednisolone
- Development stage
- Unknown
- Lead developer
- Boehringer Ingelheim
- Modality
- Small Molecules
- Administration
- Inhalation, Oral, Intravenous
01
Overview
A combination therapy consisting of albuterol (a short-acting beta-2 agonist bronchodilator), ipratropium bromide (an anticholinergic bronchodilator), and methylprednisolone (a systemic corticosteroid). This triple therapy works through complementary mechanisms to manage respiratory conditions: albuterol relaxes bronchial smooth muscle by stimulating beta-2 receptors, ipratropium blocks muscarinic cholinergic receptors to prevent bronchoconstriction, and methylprednisolone reduces airway inflammation. The combination is particularly effective for acute exacerbations of COPD and severe asthma attacks.
02
Targets
mAChR (Muscarinic acetylcholine receptors)GR (Glucocorticoid receptor)ADRB2 (β2)
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