Drug intelligence / Profile preview

albuterol sulfate + aspirin + nitroglycerin + epinephrine + dextrose + diphenhydramine

Development stage
Unknown
Lead developer
Best Dental Kit
Modality
Small Molecules
Administration
Inhalation, Intramuscular, Oral, Sublingual
01

Overview

**Albuterol sulfate + aspirin + nitroglycerin + epinephrine + dextrose + diphenhydramine** is a co-packaged dental-office emergency medication kit marketed by Best Dental Kit. The kit contains separately packaged small-molecule medicines for several acute emergencies: epinephrine for Type I allergic reactions and anaphylaxis; albuterol for bronchospasm; diphenhydramine for histamine-mediated allergic symptoms; nitroglycerin and aspirin for suspected ischemic cardiac events; and dextrose for hypoglycemia. Epinephrine is the key component for the stated anaphylaxis-related use and acts as a non-selective alpha- and beta-adrenergic receptor agonist. The Basic and Deluxe Dental Emergency Kit products are listed in DailyMed; the Deluxe kit additionally includes pediatric epinephrine and liquid diphenhydramine presentations. The product labeling has not been approved by the FDA as safe and effective.

Brand names
Basic Dental Emergency KitDeluxe Dental Emergency Kit
Other names
albuterol sulfate + aspirin + dextrose + diphenhydramine hydrochloride + epinephrine + nitroglycerinDental Emergency Kit
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)HRH1 (Histamine H1 Receptor)ADRA2A (α2A)ADRA1A (α1A)ADRB2 (β2)ADRB1 (β1)sGC (Soluble Guanylyl Cyclase)PGHS-1 (Prostaglandin G/H Synthase 1)

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