Drug intelligence / Profile preview

Albuvir

Development stage
Preclinical
Lead developer
NanoGel
Modality
Nanoparticles → Drug Delivery Systems, Peptides
Administration
Oral
01

Overview

Albuvir is a broad-spectrum antiviral agent developed by nanoigel, currently in preclinical development for the treatment of various viral infections in warm-blooded animals, including influenza, coronavirus, and herpesvirus. The drug is composed of combinatorial oligopeptide derivatives that function by interfering with the nuclear import and export of the viral genome. Specifically, it targets the Nuclear Localization Signal (NLS) complex, which is essential for the transport of viral genetic material into and out of the host cell nucleus. By disrupting this critical step in the viral replication cycle, Albuvir prevents the virus from utilizing the host's nuclear machinery, thereby inhibiting viral proliferation across diverse viral families. The technology is often formulated using a nanogel (nanoigel) delivery system to enhance stability and uptake.

Brand names
Albuvir
Other names
Albuvir-nanoigelNLS complex inhibitor
02

Targets

KPNA1 (Importin subunit alpha-5)

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