alcohol

Alcohol, typically in the form of an ethanol or isopropyl alcohol-based spray, is a widely used topical antiseptic in clinical settings. In the context of the clinical trial sponsored by Bionorte (NCT02433327), it was utilized as a placebo control to evaluate the efficacy of ethyl chloride vapocoolant spray in reducing procedural pain. The study specifically focused on pain associated with arterial punctures for gasometry determinations in an emergency department. While alcohol is primarily indicated for skin disinfection prior to invasive procedures—acting through the non-specific denaturation of microbial proteins and the dissolution of lipid membranes—it serves as a sensory control in pain studies due to its similar application method and transient cooling sensation upon evaporation, without possessing significant anesthetic properties.

Other names

ethanolethyl alcoholisopropyl alcoholalcohol-based sprayalcohol spray