alendronate + calcitriol

**Alendronate + calcitriol** is an oral fixed-dose osteoporosis medicine marketed by Yuyu Pharma as **Maxmarvil**. Each enteric-coated tablet contains alendronate sodium equivalent to 5 mg alendronic acid plus 0.5 micrograms calcitriol. Alendronate is a nitrogen-containing bisphosphonate that suppresses osteoclast-mediated bone resorption through inhibition of farnesyl pyrophosphate synthase, while calcitriol is the active form of vitamin D that activates the vitamin D receptor and supports calcium-phosphate homeostasis and bone mineralization. The product is used for osteoporosis and has been studied for prevention of aromatase inhibitor-associated bone loss in postmenopausal women with hormone receptor-positive early breast cancer. ([yuyu.co.kr](https://yuyu.co.kr/en/productInfo/productView/2/))

Brand names

Maxmarvil

Other names

alendronate + calcitriolalendronate and calcitriolalendronate/calcitriolcalcitriol + alendronate