Drug intelligence / Profile preview

Alfacyte

Development stage
Unknown
Lead developer
ILC Therapeutics
Modality
Interferons → Cytokines & Interferons → Recombinant Proteins and Enzymes
Administration
Inhalation
01

Overview

Alfacyte is a novel, synthetic hybrid interferon developed by ILC Therapeutics as a broad-spectrum antiviral treatment. It is designed as an inhaled medicine to treat respiratory viral infections (RVIs), including SARS-CoV-2 (COVID-19) and Respiratory Syncytial Virus (RSV). The drug is an engineered protein that combines properties of different interferon subtypes to enhance potency and reduce side effects compared to naturally occurring interferons. Preclinical studies at the University of St Andrews demonstrated high potency against SARS-CoV-2 in vitro. The development program includes manufacturing scale-up with 3P Bio SA and clinical trial preparation with TCRS.

Brand names
Alfacyte
Other names
Alfacytehybrid interferonsynthetic hybrid interferon
02

Targets

IFNAR (Immune system modulation via type I interferon receptor)

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