Drug intelligence / Profile preview

alfuzosin

Development stage
Approved
Lead developer
Sanofi
Modality
Small Molecules
Administration
Oral
01

Overview

Alfuzosin is an alpha-1 adrenergic antagonist (alpha blocker) used to treat the symptoms of benign prostatic hyperplasia (BPH) in adult men. It works by selectively relaxing the smooth muscle in the prostate and bladder neck through antagonism of alpha-1 adrenergic receptors. This action improves urine flow and reduces BPH symptoms such as difficulty urinating and urinary frequency or urgency. Alfuzosin does not shrink the prostate but helps relieve associated urinary symptoms. It was first approved by regulatory agencies in 2003 and is marketed globally under various brand names[1][3][5][7].

Brand names
UroxatralXatralFualZofuAlfusinAlfooProfuzoEfzu ExtFlotralXelfloAlfuzin
Other names
alfuzosina (various international markets)alfuzosine
02

Targets

ADRA1A (α1A)

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