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ALG-001024

Development stage: Preclinical
Lead developer: Aligos Therapeutics
Modality: Small Molecules
Administration: Oral

Overview

ALG-001024 is an investigational **small-molecule hepatitis B virus capsid assembly modulator** being developed by Aligos Therapeutics for chronic hepatitis B. Preclinical reports describe it as a potent, pangenotypic inhibitor of HBV replication that drives aberrant or empty capsid assembly and inhibits HBV DNA production, while also showing activity against RNA encapsidation and the establishment or replenishment of covalently closed circular DNA. Available public information indicates that the program remained at the **preclinical** stage and does not appear to have advanced into registered clinical development.

Targets

HBc (Hepatitis B virus core protein)

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