Drug intelligence / Profile preview

ALGRX 3268

Development stage
Phase 4
Lead developer
AlgoRx Pharmaceuticals
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Intradermal, Cutaneous
01

Overview

ALGRX 3268 is a novel, single-use, prefilled, needle-free drug delivery system designed to provide rapid local anesthesia for minor procedures such as venipuncture and intravenous line placement. The device delivers powdered lidocaine into the epidermis using a gas-powered injector (PowderJect technology), achieving local analgesia within approximately one to three minutes. This fast onset distinguishes it from traditional topical anesthetics that require significantly longer application times. The product was primarily developed for pediatric patients but may also be useful in adult emergency settings and other clinical environments where quick pain relief is needed before needle insertion. Clinical trials demonstrated that ALGRX 3268 significantly reduces pain associated with needlestick procedures compared to placebo and is well tolerated with no significant safety issues[1][2][4][5][6][7][9].

Brand names
ALGRX 3268ALGRX3268ALGRX-3268PowderJect Dermal Lidocaine
Other names
ALGRX 3268ALGRX3268ALGRX-3268PowderJect Dermal Lidocaine
02

Targets

SCN1A (Voltage-gated sodium channel protein type 1 subunit alpha)

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