Drug intelligence / Profile preview

alisol b 23-acetate

Development stage: Preclinical
Modality: Small Molecules
Administration: Intragastric, Oral, Intranasal

Overview

Alisol B 23-acetate is a **natural protostane-type triterpenoid small molecule** isolated from *Alisma* species that has been investigated in preclinical research for metabolic disease, particularly obesity and related disorders. In the cited mouse study, it promoted white adipose tissue browning and improved high-fat diet-induced obesity, with reported activity linked to regulation of the **mTOR-SREBP1 signaling axis**. The compound appears to remain an experimental research-stage agent rather than a clinically developed pharmaceutical product, and no specific commercial developer, approved indication, or branded product could be reliably identified from the provided evidence.

Other names: alisol b 23-acetateAB23AAB-23AAB 23A

Targets

SREBP-1 / SREBF1 (SREBP-1)SIRT1 (NAD-dependent protein deacetylase sirtuin-1)mTOR (Mammalian target of rapamycin kinase)ESR1 (ERα)

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