alkaline glucosodiene

Alkaline glucosodiene is a novel compound described as an alkaline isomer or polymer of glucose, synthesized by reacting dextrose (glucose) with sodium bicarbonate. The resulting molecule, identified as 1-2-O-β-D-Glucopyranosyl-α-D-glucose (C12H22O11), forms a polymer through 1-2 linkages and exhibits properties distinct from native glucose. Its proposed mechanism of action targets cancer cell metabolism—specifically the Warburg effect—by exploiting cancer cells' high avidity for glucose. When taken up by tumor cells via their glucose transporters, the modified structure and alkalinity are hypothesized to disrupt cellular metabolism and pH balance, leading to selective cytotoxicity in cancerous tissue while sparing normal cells. Preclinical studies and early case reports suggest potential efficacy in solid tumors such as triple-negative breast cancer with bone metastasis; however, its chemical structure requires further validation and clinical evidence remains limited[1][3][4][5][6][7].

Other names

glucosodieneglucosodiene polymeralkaline glucose isomer