Drug intelligence / Profile preview

Alkindi Sprinkle

Development stage
Approved
Lead developer
Eton Pharmaceuticals
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Alkindi Sprinkle is a pediatric-specific, immediate-release oral formulation of hydrocortisone, a synthetic glucocorticoid. It is indicated as replacement therapy for adrenocortical insufficiency in infants, children, and adolescents from birth to 17 years of age. Hydrocortisone acts by mimicking endogenous cortisol, exerting metabolic effects and modulating immune responses. The granular formulation allows for precise low-dose titration and easy administration by sprinkling on food or directly into the mouth—addressing challenges with dosing accuracy in young children who cannot swallow tablets. Alkindi Sprinkle is the first FDA-approved granular hydrocortisone product specifically designed for pediatric use[1][4][5][6][8].

Brand names
Alkindi Sprinkle
Other names
hydrocortisone oral granules
02

Targets

MR (Mineralocorticoid receptor)GR (Glucocorticoid receptor)

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