Drug intelligence / Profile preview

allantoin + coal tar + clioquinol + triclosan

Development stage
Unknown
Lead developer
Laboratorios Silanes
Modality
Small Molecules
Administration
Topical
01

Overview

This drug is a **topical combination medication** consisting of allantoin, coal tar, clioquinol, and triclosan, each with distinct dermatological actions. **Allantoin** is known for its keratolytic and skin-soothing properties, promoting wound healing and epithelialization. **Coal tar** acts as a keratolytic, anti-inflammatory, and antimicrobial agent, slowing excessive skin cell proliferation, reducing itching, inflammation, and scaling, and is frequently prescribed for chronic skin conditions like psoriasis and eczema[1][3][5][7]. **Clioquinol** is a halogenated hydroxyquinoline with antimicrobial and antifungal properties, often used in treating skin infections and inflammatory dermatoses. **Triclosan** is a broad-spectrum synthetic antimicrobial agent effective against bacteria and fungi; it is included in personal care and medical products primarily for its bactericidal, fungicidal, and biocidal activities[2][4][8]. This combination is primarily indicated for the topical treatment of dermatological conditions—such as psoriasis, eczema, seborrheic dermatitis, fungal or bacterial skin infections—where antimicrobial, anti-inflammatory, and keratolytic activities are required.

02

Targets

Zn2+ (Zinc ion)InhAAcrB

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