allenrolfea occidentalis pollen extract

Allenrolfea occidentalis pollen extract is a biological allergen used for the diagnosis and treatment of Type I hypersensitivity reactions to iodine bush pollen. Iodine bush is a halophytic shrub common in the arid regions of the Southwestern United States and Mexico. The extract contains a complex mixture of proteins that, when administered in small amounts during skin testing, can identify sensitized individuals by eliciting a wheal-and-flare reaction. In therapeutic settings, the extract is used in allergen-specific immunotherapy (SIT), where increasing doses are administered subcutaneously to induce immunological tolerance. This process involves shifting the immune response from a Th2-mediated allergic profile to a Th1 or regulatory T-cell (Treg) profile, increasing the production of IgG4 blocking antibodies, and reducing the sensitivity of mast cells and basophils to the allergen.

Other names

Iodine bush pollen extractPickleweed pollen extractAllenrolfea occidentalis pollen