Drug intelligence / Profile preview

allergen extract (Anallergo SLIT)

Development stage
Unknown
Lead developer
ANALLERGO
Administration
Sublingual
01

Overview

Sublingual immunotherapy (SLIT) by Anallergo is an allergen-specific immunotherapy product designed to treat allergic diseases such as allergic rhinitis and asthma. The therapy involves administering small doses of specific allergens under the tongue in the form of drops or tablets, with the goal of inducing immune tolerance to those allergens over time. The mechanism of action relies on promoting a shift from a Th2-dominated immune response (which drives allergy symptoms) toward a Th1/regulatory T cell response, increasing production of anti-inflammatory cytokines like IL-10 and TGF-beta. This leads to reduced sensitivity to allergens and decreased symptoms upon exposure[6][8]. Allergen-specific IgG and IgA antibodies are also induced, which block allergen-IgE complex formation[6]. Anallergo develops customized formulations for individual patients based on their specific allergies[1].

Brand names
Anallergo SLIT
Other names
Anallergo SLITsublingual immunotherapySLIT
02

Targets

γδ TCR (T-cell receptor)BCR (Immunoglobulin G B Cell Receptor)MHC II (Major histocompatibility complex class II receptor)

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