Drug intelligence / Profile preview

allergenic extract- beef liver

Development stage
Unknown
Lead developer
Ares Life Sciences
Modality
Recombinant Proteins and Enzymes
Administration
Percutaneous, Intradermal
01

Overview

Allergenic extract- beef liver is a sterile biologic solution derived from bovine liver tissue, primarily utilized as a diagnostic tool in clinical allergy testing. It is administered via percutaneous (prick/puncture) or intradermal skin testing to identify IgE-mediated hypersensitivity in patients suspected of having an allergy to beef liver. The extract contains the protein components of the liver that act as allergens; when introduced into the skin of a sensitized individual, these proteins cross-link specific IgE antibodies bound to the surface of mast cells and basophils. This interaction triggers the release of inflammatory mediators such as histamine, resulting in a localized wheal-and-flare reaction. The product is intended for use by healthcare professionals experienced in the administration of allergenic extracts and the emergency management of potential anaphylaxis.

Other names
beef liver extractbeef liver allergenic extract
02

Targets

α-Gal-specific IgE (Galactose-α-1,3-galactose-specific IgE)High-affinity immunoglobulin epsilon receptor-bound Immunoglobulin E complex

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