Drug intelligence / Profile preview

allergovac poliplus

Development stage
Phase 1
Lead developer
Roxall Medizin
Modality
Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
Administration
Subcutaneous
01

Overview

Allergovac Poliplus is a subcutaneous immunotherapy (SCIT) product developed by Roxall Medicina España (ROXALL Medizin) for the treatment of polysensitized patients. It consists of a polymerized-depot formulation containing a mixture of two allergenic extracts, typically derived from pollens (such as *Olea europaea* and *Phleum pratense*) or mites. The polymerization process, often using glutaraldehyde, is designed to reduce the allergenicity of the extracts to improve safety and tolerability while maintaining their immunogenicity. The drug is indicated for patients with allergic rhinitis or rhinoconjunctivitis, with or without associated mild-to-moderate asthma. It is administered via subcutaneous injection using either a one-day rapid schedule or a traditional dose-escalation initiation period followed by maintenance therapy.

Brand names
Allergovac Poliplus
Other names
Allergovac Poliplus SCIT
02

Targets

IL10 (Interleukin-10)A. annua-specific IgE (Artemisia annua-specific immunoglobulin E)

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