Drug intelligence / Profile preview

allisartan medoxomil

Development stage
Unknown
Lead developer
Shenzhen Salubris Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

Allisartan medoxomil is a small molecule prodrug developed by Shenzhen Salubris Pharmaceuticals Co., Ltd. It is an angiotensin II receptor blocker (ARB) primarily indicated for the treatment of essential hypertension. As a prodrug, it is hydrolyzed to its active metabolite, alisartan (also known as EXP3174), which selectively blocks the angiotensin II type 1 (AT1) receptor. This action leads to vasodilation and a reduction in blood pressure. Allisartan medoxomil is administered orally.

Brand names
信立坦
Other names
Alisartan阿利沙坦酯Olisartan medoxomil
02

Targets

AGTR1 (Angiotensin II Type-1 receptor)

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