Drug intelligence / Profile preview

Allium cepa

Development stage
Phase 4
Administration
Oral, Topical, Intranasal
01

Overview

Allium cepa, commonly known as onion, is a widely consumed plant with significant culinary and medicinal uses. In traditional and complementary medicine, it is used for its broad pharmacological properties including antioxidant, anti-inflammatory, antihypertensive, antidiabetic, and immunomodulatory effects. The main active constituents include flavonoids (such as quercetin and kaempferol), thiosulfinates, alk(en)yl cysteine sulfoxides (e.g., S-methyl cysteine sulfoxide), cycloalliin, phenolic acids, anthocyanins, saponins, and various sulfur-containing compounds. Allium cepa has been studied for its potential benefits in respiratory disorders (such as asthma and bronchitis), allergic conditions (including nasal allergies), wound healing (scarring and keloids), metabolic disorders like obesity and diabetes mellitus type 2, hypertension, hair loss prevention/treatment in cosmetics formulations such as onion extract gels or oils for topical use. In homeopathy under the name "Allium Cepa," it is primarily used to relieve symptoms of runny nose with clear discharge due to colds or allergies[1][3][4][5][7].

Brand names
Allium Cepa
Other names
onion
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)HRH1 (Histamine H1 Receptor)

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