allogeneic adipose-derived mesenchymal stem cells + fibrin gel

This cell-based regenerative therapy, developed by the Medical University of Warsaw, consists of allogeneic adipose-derived mesenchymal stem cells (ADSCs) suspended in a fibrin gel matrix for the treatment of chronic wounds in diabetic foot syndrome. The therapy, often referred to in clinical contexts as 1ABC Therapy, involves applying the ADSC-fibrin suspension directly onto the prepared wound bed, where it polymerizes into a thin gel layer. The ADSCs function by secreting a variety of pro-angiogenic and anti-inflammatory cytokines and growth factors, which modulate the chronic wound microenvironment to promote tissue repair, reduce inflammation, and accelerate epithelialization in patients with diabetic foot ulcers.

Other names

ADSC in fibrin gelallogeneic ADSC + fibrin solutionadipose-derived stem cells + fibrin gel