Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
allogeneic ex-vivo expanded bone marrow-derived mesenchymal stem cells
- Development stage
- Unknown
- Lead developer
- Odense Universitetshospital
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intraarticular
01
Overview
Allogeneic ex-vivo expanded bone marrow-derived mesenchymal stem cells (BM-MSCs) are an investigational cell therapy developed by Odense University Hospital for the treatment of knee osteoarthritis. These cells are harvested from healthy donors, expanded in vitro to reach therapeutic quantities, and then administered via intra-articular injection. The therapy functions primarily through paracrine signaling, where the cells secrete a variety of anti-inflammatory cytokines and growth factors (the secretome) that modulate the local immune environment and inhibit synovial inflammation. This approach aims to provide a standardized, 'off-the-shelf' therapeutic option that overcomes the donor-age and potency limitations often associated with autologous stem cell treatments.
- Other names
- allogeneic bone marrow-derived mesenchymal stem cellsallogeneic BM-MSCs
Beyond the preview
Go deeper on allogeneic ex-vivo expanded bone marrow-derived mesenchymal stem cells.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on allogeneic ex-vivo expanded bone marrow-derived mesenchymal stem cells.