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allogeneic fecal microbiota
- Development stage
- Approved
- Lead developer
- Ferring Pharmaceuticals
- Modality
- Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
- Administration
- Oral, Rectal, Nasogastric, Nasoduodenal, Intraduodenal
01
Overview
Allogeneic fecal microbiota is a therapeutic approach that involves transplanting fecal matter from a healthy donor into the gastrointestinal tract of a recipient to restore gut microbiota diversity and function. The procedure directly modifies the host gut microbiome composition to restore diversity and gut homeostasis. It can be delivered via various routes including the upper gastrointestinal tract (using esophagogastroduodenoscopy, nasogastric or nasoduodenal tube, oral capsule) or lower gastrointestinal tract (via colonoscopy or enema). The source of fecal material is from a related or unrelated healthy donor (allogeneic), as opposed to autologous FMT where the patient's own previously collected stool is used.
- Brand names
- REBYOTAVOWST
- Other names
- FMTfecal microbiota transplantationfecal microbiota transferstool transplantbacteriotherapyintestinal microbiota transplantfecal microbiota live-jslm
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