allogeneic tumor-derived lymphocyte therapy

Allogeneic tumor-derived lymphocyte therapy is a form of cellular immunotherapy that uses lymphocytes derived from tumor tissue of donors (rather than the patient's own cells) to target and eliminate cancer cells. This approach involves collecting, isolating, and potentially engineering lymphocytes from donor tumor tissue before infusing them into patients. The therapy often requires lymphodepletion before administration to prevent rejection and enhance efficacy. Clinical trials have shown promising results in treating various cancers, particularly hematologic malignancies like acute myeloid leukemia (AML).

Other names

Allogeneic Cell Therapy with Tumor-derived Lymphocytesallogeneic γδ T cell therapyallogeneic Vγ9Vδ2 T cells