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allogeneic umbilical cord mesenchymal stem cell + adipose secretome
- Development stage
- Unknown
- Lead developer
- Universitas Indonesia
- Modality
- Cell Therapies, Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
- Administration
- Intravenous, Intrathecal
01
Overview
This combination biologic therapy consists of allogeneic mesenchymal stem cells derived from the umbilical cord (UC-MSCs) and the secretome (a collection of paracrine factors, including exosomes, cytokines, and growth factors) derived from adipose tissue. UC-MSCs provide potent immunomodulatory and regenerative properties, while the adipose secretome provides a concentrated cocktail of growth factors and anti-inflammatory mediators to enhance the therapeutic microenvironment. This combination has been primarily investigated for conditions involving severe systemic inflammation and tissue damage, such as COVID-19-induced pneumonia and Acute Respiratory Distress Syndrome (ARDS), where it aims to suppress the cytokine storm and promote lung tissue repair.
- Other names
- Allogeneic Umbilical Cord Mesenchymal Stem Cell + Adipose SecretomeUC-MSC + Adipose Secretome
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